CALTOX

CALTOX

Calcium, Magnesium, Zinc with Calcitriol Tablet
Net Qty- 15 Tablets
Self-Life- 2 Years

💊 Caltox is combination of Calcium, Magnesium, Zinc with Calcitriol

This combination tablet is a nutritional supplement used to maintain healthy bones, teeth, muscles, and immune function. It is commonly prescribed for conditions like osteoporosis, osteopenia, calcium deficiency, and vitamin D disorders.

🔍 Composition:

  • Calcium Carbonate – Provides elemental calcium for bone strength.
  • Magnesium – Supports nerve, muscle, and enzyme function.
  • Zinc – Essential for immunity and tissue repair.
  • Calcitriol (Active Vitamin D3) – Helps in absorption of calcium and phosphorus from the gut.

✅ Common Uses:

  • Osteoporosis and bone loss
  • Calcium & Vitamin D deficiency
  • Post-menopausal bone health
  • Fracture healing
  • Hypocalcemia (low blood calcium levels)
  • Muscle cramps due to deficiency

USE

✅ Uses of Caltox (Calcium, Magnesium, Zinc with Calcitriol Tablet)

This combination is widely used to support bone health, improve calcium absorption, and correct mineral deficiencies. It’s particularly helpful in individuals with poor dietary intake, elderly patients, and those with bone disorders.

🩺 Medical Uses:

  1. Osteoporosis & Osteopenia
    • Strengthens bones, reduces fracture risk.
  2. Calcium & Vitamin D3 Deficiency
    • Improves absorption of calcium through Calcitriol, the active form of Vitamin D.
  3. Postmenopausal Bone Health
    • Helps reduce bone loss in women after menopause.
  4. Fracture Recovery
    • Promotes faster bone healing.
  5. Muscle Cramps & Spasms
    • Calcium and magnesium help in neuromuscular function.
  6. Hypocalcemia (Low Calcium Levels)
    • Effective in treating and preventing calcium deficiency symptoms.
  7. Chronic Kidney Disease (CKD)
    • Often used in patients to regulate calcium-phosphate balance, under medical supervision.
  8. Improving Immunity
    • Zinc contributes to better immune response and wound healing.

Key Ingredients

🟢 Composition of Caltox Tablet

Each Tablet typically contains a combination of:

  • Calcium Carbonate – Provides elemental calcium for bone strength.
  • Magnesium – Supports nerve, muscle, and enzyme function.
  • Zinc – Essential for immunity and tissue repair.
  • Calcitriol (Active Vitamin D3) – Helps in absorption of calcium and phosphorus from the gut.

Key Benefits

🌟 Key Benefits of Caltox (Calcium, Magnesium, Zinc with Calcitriol Tablet)

This nutritional supplement offers a powerful blend of essential minerals and active vitamin D3, making it ideal for bone, muscle, and immune health.

✅ Enhances Bone Strength & Density

  • Calcium strengthens bones and teeth.
  • Calcitriol (active Vitamin D3) helps absorb calcium effectively.
  • Helps prevent osteoporosis, osteopenia, and fractures.

✅ Supports Muscle Health

  • Magnesium improves muscle function and prevents cramps or spasms.
  • Aids in nerve signaling and muscle relaxation.

✅ Boosts Immunity

  • Zinc enhances immune system response and helps in wound healing.
  • Essential for fighting off infections and maintaining overall vitality.

✅ Aids in Faster Recovery from Fractures

  • Promotes healing of broken bones and strengthens joints post-injury or surgery.

✅ Maintains Calcium-Phosphorus Balance

  • Especially useful in patients with chronic kidney disease to regulate mineral balance.

✅ Reduces Risk of Deficiency Disorders

  • Prevents and treats hypocalcemia, vitamin D deficiency, magnesium deficiency, and zinc deficiency.

Mechanism
of Action

🧬 Mechanism of Action of Caltox (Calcium, Magnesium, Zinc with Calcitriol Tablet)

This supplement combines key minerals and active vitamin D3 (Calcitriol) to work synergistically in maintaining bone and overall health. Here’s how each component functions:

 

 

🔹 Calcitriol (Active Vitamin D3):

  • Increases absorption of calcium and phosphorus from the intestine.
  • Promotes bone mineralization by maintaining optimal blood calcium levels.
  • Enhances renal (kidney) reabsorption of calcium.
  • Helps regulate parathyroid hormone (PTH), reducing bone resorption (breakdown).

🔹 Calcium Carbonate:

  • Provides elemental calcium, a key structural component of bones and teeth.
  • Supports neuromuscular function, blood clotting, and hormone release.
  • Calcium absorption is enhanced by Calcitriol.

🔹 Magnesium:

  • Acts as a cofactor for over 300 enzymatic reactions in the body.
  • Helps in converting vitamin D into its active form (Calcitriol).
  • Regulates muscle contraction, nerve function, and heart rhythm.
  • Works with calcium to maintain bone density.

🔹 Zinc:

  • Plays a crucial role in bone tissue renewal, immune function, and cell repair.
  • Promotes the action of enzymes required for collagen formation in bones.
  • Enhances wound healing and resistance to infections.

🔁 Synergistic Action:

Together, these nutrients complement each other to:

  • Improve calcium absorption and retention
  • Strengthen bones and muscles
  • Support immune health and cellular function

Dosage and Administration

💊 Dosage and Administration of Caltox (Calcium, Magnesium, Zinc with Calcitriol Tablet)

This supplement is used to support bone health, correct mineral deficiencies, and aid in conditions like osteoporosis or calcium/vitamin D3 deficiency. It should be taken under medical supervision, especially in patients with kidney disorders or other chronic illnesses.

 

✅ Recommended Dosage:

  • Adults:
    ➤ 1 tablet once or twice daily (as advised by a physician)
    ➤ Preferably after meals to enhance absorption and minimize gastric discomfort
  • Children / Elderly:
    ➤ Only if prescribed by a healthcare provider
    ➤ Dosing varies based on individual nutritional needs and health conditions

📌 Administration Guidelines:

  • Oral route: Swallow the tablet whole with a full glass of water
  • Do not crush or chew the tablet
  • Take at fixed times daily for best results
  • Avoid taking with high-iron supplements or antacids simultaneously (may interfere with absorption)
  • Maintain adequate hydration and a balanced diet

⚠️ Missed Dose:

  • Take it as soon as you remember
  • If it’s close to the next dose, skip the missed dose
  • Do not double the dose

⚠️ Storage:

  • Store in a cool, dry place below 25°C
  • Keep away from moisture and direct sunlight

Common Side Effects

⚠️ Common Side Effects of Caltox (Calcium, Magnesium, Zinc with Calcitriol Tablet)

While this supplement is generally well-tolerated, some individuals may experience mild side effects, especially if taken in high doses or without medical supervision.

 

🔹 Gastrointestinal Side Effects:

  • Nausea
  • Stomach upset
  • Constipation
  • Bloating
  • Metallic taste in the mouth

🔹 Hypercalcemia Symptoms (Too much calcium in blood) (rare, usually due to overdose):

  • Weakness or fatigue
  • Excessive thirst or frequent urination
  • Muscle pain
  • Confusion or mood changes
  • Vomiting or abdominal pain

🔹 Magnesium-related Effects (in excessive intake):

  • Diarrhea
  • Soft stools
  • Abdominal cramping

🔹 Zinc-related Effects (in excessive or long-term use):

  • Loss of appetite
  • Headache
  • Copper deficiency (rare)

🔹 Allergic Reactions (very rare):

  • Skin rash
  • Itching or swelling
  • Breathing difficulty

⚠️ If any severe or persistent symptoms occur, consult your doctor immediately.

Monitoring

🔍 Monitoring of Caltox (Calcium, Magnesium, Zinc with Calcitriol Tablet)

Proper monitoring ensures safe and effective use of this mineral and vitamin D3 combination, especially in individuals with chronic conditions or long-term supplementation.

✅ Serum Calcium Levels

  • Regular monitoring to detect hypercalcemia (excess calcium), especially in:
    • Kidney disease
    • Hyperparathyroidism
    • Elderly patients
  • Normal range: ~8.5–10.2 mg/dL
  • High levels may require dose adjustment or discontinuation

✅ Serum Magnesium and Zinc Levels

  • Checked periodically during long-term use
  • Ensures proper mineral balance and avoids toxicity or deficiency

✅ Serum Phosphorus

  • Especially if patient has renal impairment
  • Helps assess bone mineralization and kidney function balance

✅ Renal (Kidney) Function Tests

  • Especially in patients with:
    • Chronic kidney disease (CKD)
    • Diabetes
    • Elderly
  • Monitor BUN, Creatinine, and eGFR

✅ Vitamin D Levels (25-hydroxyvitamin D)

  • Evaluates if additional vitamin D3 is needed or if levels are too high
  • Normal range: 20–50 ng/mL

✅ Parathyroid Hormone (PTH) – if indicated

  • Monitored in patients with bone disorders, kidney disease, or on calcitriol therapy

⚠️ Monitoring should be more frequent in:

  • Elderly
  • Pregnant or breastfeeding women
  • Those with malabsorption, liver, or kidney disease
  • Patients on other supplements or medications

Precautions

⚠️ Precautions of Caltox (Calcium, Magnesium, Zinc with Calcitriol Tablet)

This supplement is generally safe when used appropriately, but certain precautions should be taken, especially in people with underlying health conditions.

✅  Avoid Overdose

  • Do not exceed the recommended dose unless prescribed by a doctor.
  • Excessive intake may lead to hypercalcemia or magnesium/zinc toxicity.

✅  Kidney Disorders

  • Use with caution in patients with kidney disease, especially those with:
    • Chronic kidney disease (CKD)
    • Kidney stones
  • Risk of calcium and phosphorus imbalance is higher.

✅  Heart Conditions

  • High calcium or magnesium levels can affect heart rhythm.
  • Monitor closely if patient is on cardiac medications (e.g., digoxin).

✅  Pregnancy and Breastfeeding

  • Safe when used within recommended dietary allowances (RDA).
  • Avoid megadoses without medical advice.

✅  Drug Interactions

  • May interact with:
    • Antibiotics (e.g., tetracyclines, quinolones)
    • Thyroid medications (e.g., levothyroxine)
    • Iron supplements (space dosing)
    • Diuretics (increased calcium levels)
  • Take these medications at least 2 hours apart from this supplement.

✅  Malabsorption Syndromes

  • People with intestinal absorption issues may require modified dosing or different formulations.

✅  Liver Disease

  • Use with caution in severe liver disease, as metabolism of vitamin D and zinc may be altered.

✅  Allergies

  • Check for allergic reactions to any ingredient (e.g., colorants, preservatives, gelatin in capsules).

Drug Interactions

💊 Drug Interactions of Caltox (Calcium, Magnesium, Zinc with Calcitriol Tablet)

This supplement may interact with several medications, affecting either absorption or effectiveness, or causing toxicity when combined.

⚠️  Antibiotics (Reduced Absorption)

  • Tetracyclines (e.g., doxycycline, tetracycline)
  • Quinolones (e.g., ciprofloxacin, levofloxacin)
    🕒 Take 2–4 hours apart to avoid reduced antibiotic absorption.

⚠️  Thyroid Medications

  • Levothyroxine
    – Calcium and magnesium may reduce absorption
    🕒 Take 4 hours apart

⚠️  Iron, Zinc, and Other Mineral Supplements

  • Compete for absorption in the gut
    🕒 Space doses by 2–3 hours to maximize efficacy

⚠️  Diuretics

  • Thiazide diuretics (e.g., hydrochlorothiazide):
    ⬆️ Increase calcium levels → risk of hypercalcemia
  • Loop diuretics (e.g., furosemide):
    ⬇️ Can lead to calcium & magnesium loss → electrolyte imbalance

⚠️  Digoxin (Heart Medication)

  • High calcium levels can enhance digoxin toxicity
    💓 Monitor ECG and serum calcium

⚠️  Antacids Containing Aluminum

  • Calcitriol increases aluminum absorption → risk of bone toxicity
    – Use only under medical supervision in kidney patients

⚠️  Corticosteroids (e.g., prednisone)

  • May reduce calcium absorption → decreased supplement efficacy
    – Higher doses or additional vitamin D may be needed

⚠️  Antiepileptics (e.g., phenytoin, carbamazepine)

  • Can lower vitamin D levels → may require dosage adjustment

✅ General Tip:

To avoid most interactions, take this supplement at least 2 hours apart from other medications.

Clinical Effectiveness

✅ Clinical Effectiveness of Caltox (Calcium, Magnesium, Zinc with Calcitriol Tablet)

This combination supplement has been proven effective in clinical practice for improving bone health, mineral balance, and supporting metabolic functions, especially in populations at risk of nutritional deficiencies.

🦴  Improves Bone Mineral Density (BMD)

  • Calcium + Calcitriol (active vitamin D3) enhances calcium absorption in the intestines and promotes bone formation.
  • Especially effective in osteoporosis, osteopenia, and postmenopausal women.

💪  Supports Muscle Function & Reduces Cramping

  • Magnesium plays a crucial role in neuromuscular transmission and muscle relaxation.
  • Helps prevent muscle cramps, particularly in elderly and pregnant individuals.

🧠  Enhances Nerve & Enzyme Function

  • Zinc contributes to cellular enzyme systems, immune response, and wound healing.
  • Magnesium supports neurotransmitter function and reduces neurological irritability.

🌞 Corrects Vitamin D Deficiency

  • Calcitriol, the active form of Vitamin D3, is rapidly bioavailable, even in patients with kidney or liver disease, where Vitamin D activation is impaired.
  • Useful in conditions like chronic kidney disease (CKD) and hypoparathyroidism.

🧬  Regulates Mineral Homeostasis

  • Maintains proper levels of calcium, magnesium, phosphorus, and zinc, preventing deficiency-related complications.

🤰  Supports Pregnancy & Lactation Needs

  • Clinically used in pregnancy to support fetal bone development and maternal health.

💊 Evidence-Based Use in:

  • Osteoporosis
  • Rickets/Osteomalacia
  • Postmenopausal bone loss
  • Elderly with poor dietary intake
  • Muscle cramps or weakness
  • Chronic kidney disease (CKD)
  • Recovery from fractures

🔬 Clinical trials and post-marketing studies confirm the synergistic effect of combining these minerals with active vitamin D in improving bone and immune health, especially when dietary intake is insufficient.

Tips for Patients

📝 Tips for Patients Taking Calcium, Magnesium, Zinc with Calcitriol Tablet

To get the maximum benefit and minimize side effects, follow these patient-friendly tips:

💊  Take with Food

  • Take the tablet with or after meals to enhance absorption and reduce stomach upset.

⏰  Maintain Timing Gaps

  • Avoid taking with other medications like antibiotics, thyroid meds, or iron supplements.
    ➤ Maintain a 2–4 hour gap for better absorption.

💧  Stay Hydrated

  • Drink plenty of water throughout the day to help kidney function and prevent constipation.

🌞  Get Some Sunlight

  • Moderate sun exposure (15–20 mins a day) can boost your vitamin D levels naturally.

⚖️  Don’t Exceed the Prescribed Dose

  • Taking too much calcium or vitamin D can cause hypercalcemia, kidney issues, or other complications.

📋  Inform Your Doctor If You Have:

  • Kidney problems
  • Heart disease
  • Hypercalcemia (high calcium levels)
  • On other medications like diuretics, digoxin, or steroids

🧪  Monitor Blood Levels (if long-term use)

  • Regular checkups may be needed to track:
    • Calcium
    • Vitamin D
    • Kidney function

🚫  Avoid Certain Foods/Supplements at the Same Time

  • High-oxalate foods (e.g., spinach), caffeine, or high-phosphorus sodas may reduce calcium absorption.
  • Avoid other supplements with high aluminum or iron content at the same time.

🧼  Store Properly

  • Keep in a cool, dry place, away from sunlight and moisture.

✅  Be Consistent

  • Take daily at the same time to develop a habit and ensure effectiveness.